Disease: Dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WASF2 Q9Y6W5 WASP family member 2 Cellular structure 0.98 0.585 0.769
VPS35 Q96QK1 VPS35 retromer complex component Transporter 0.97 0.656 0.500
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
SREBF1 P36956 sterol regulatory element binding transcription factor 1 1.5E-02 0.518 0.808
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
SNCB Q16143 synuclein beta Transporter 6.8E-02 0.619 0.577
SNCAIP Q9Y6H5 synuclein alpha interacting protein 3.3E-04 0.691 0.423
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SMPD1 P17405 sphingomyelin phosphodiesterase 1 Enzyme 3.9E-10 0.499 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SIRT2 Q8IXJ6 sirtuin 2 Epigenetic regulator 2.3E-08 0.510 0.769
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
SCARB2 Q14108 scavenger receptor class B member 2 Receptor 8.9E-05 0.606 0.615
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PON2 Q15165 paraoxonase 2 5.4E-05 0.566 0.808